5 Simple Techniques For Akorn Promethazine with codeine syrup
5 Simple Techniques For Akorn Promethazine with codeine syrup
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Breathing Issues. Promethazine/codeine might cause gradual or shallow breathing, especially if you've breathing challenges from A different issue or get other medicines that may gradual your respiration.
When you are employing a liquid kind, make use of a medication-measuring system or spoon to cautiously measure the prescribed dose. Will not utilize a home spoon simply because you may well not get the proper dose. In case your liquid form is actually a suspension, shake the bottle very well before Each and every dose.
Tend not to make use of a house teaspoon to measure your medication. Chances are you'll unintentionally acquire an excessive amount. You could check with your pharmacist for that measuring product it is best to use and how to measure the proper dose.
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Promethazine hydrochloride wasn't mutagenic from the in vitro bacterial reverse mutation assay or clastogenic during the in vitro Chinese hamster ovary (CHO) cell chromosomal aberration assay.
Promethazine: Symptoms and symptoms of overdosage with promethazine HCl range between moderate depression on the central anxious technique and cardiovascular procedure to profound hypotension,
Keep away from the usage of Promethazine HCl and Codeine Phosphate Oral Remedy in adolescents 12 to eighteen many years of age who produce other possibility variables that could improve their sensitivity to the respiratory depressant effects of codeine. Threat elements incorporate situations linked with hypoventilation, for instance postoperative status, obstructive rest apnea, weight problems, significant pulmonary condition, neuromuscular disease, and concomitant usage of other drugs that bring about respiratory despair.
Constrained information recommend that usage of promethazine hydrochloride during labor and shipping and delivery does not have an considerable impact on the period of labor or shipping and delivery and doesn't increase the risk of have to have for intervention from the read more newborn.
Remedy: The therapy of overdosage with promethazine and codeine is actually symptomatic and supportive. Only in cases of extreme overdosage or unique sensitivity do very important signals including respiration, pulse, blood pressure level, temperature, and EKG must be monitored. Activated charcoal orally or by lavage could possibly be provided, or sodium or magnesium sulfate orally being a cathartic. Focus should be provided on the more info reestablishment of satisfactory respiratory exchange by way of provision of a patent airway and institution of assisted or managed ventilation.
This determination not just addresses fears with regards to the misuse and addictive prospective of codeine linctus check here but will also underscores the significance of prioritising Akorn Promethazine with codeine syrup patient properly-becoming.
Promethazine is metabolized because of the liver to a variety website of inactive metabolites including sulfoxides of promethazine, N-demethylpromethazine and also other glucuronides.
Withdrawal signs or symptoms can come about in breastfed infants when maternal administration of the opioid is stopped, or when breastfeeding is stopped.
Codeine is known to generally be substantially excreted because of the kidney, and the potential risk of adverse reactions to this drug could possibly be better in people with impaired renal function.